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Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study

BACKGROUND: The human fibroblast growth factor (FGF) and its receptor (FGFR) play an important role in tumorigenesis. Deregulation of the FGFR2 gene has been identified in a number of cancer sites. Overexpression of the FGFR4 protein has been linked to cutaneous melanoma progression. Previous studie...

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Autori principali: Nan, Hongmei, Qureshi, Abrar A, Hunter, David J, Han, Jiali
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699349/
https://ncbi.nlm.nih.gov/pubmed/19500394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-172
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