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A Polymorphism of GRK5 Alters Agonist-Promoted Desensitization of β(2)-Adrenergic Receptors
β-agonist treatment of asthma displays substantial interindividual variation, which has prompted polymorphism discovery and characterization of β(2)-adrenergic (β(2)AR) signaling genes. β(2)AR function undergoes desensitization during persistent agonist exposure due to receptor phosphorylation by G-...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699179/ https://ncbi.nlm.nih.gov/pubmed/18622265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32830967e9 |
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