Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

Receptors involved in innate immunity to fungal pathogens have not been fully elucidated. We show that the Caenorhabditis elegans receptors CED-1 and C03F11.3, and their mammalian orthologues, the scavenger receptors SCARF1 and CD36, mediate host defense against two prototypic fungal pathogens, Cryp...

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Main Authors: Means, Terry K., Mylonakis, Eleftherios, Tampakakis, Emmanouil, Colvin, Richard A., Seung, Edward, Puckett, Lindsay, Tai, Melissa F., Stewart, Cameron R., Pukkila-Worley, Read, Hickman, Suzanne E., Moore, Kathryn J., Calderwood, Stephen B., Hacohen, Nir, Luster, Andrew D., El Khoury, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699123/
https://ncbi.nlm.nih.gov/pubmed/19237602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082109
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