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Drug Discovery Using Chemical Systems Biology: Repositioning the Safe Medicine Comtan to Treat Multi-Drug and Extensively Drug Resistant Tuberculosis

The rise of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis around the world, including in industrialized nations, poses a great threat to human health and defines a need to develop new, effective and inexpensive anti-tubercular agents. Previously we developed a chemical...

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Hlavní autoři: Kinnings, Sarah L., Liu, Nina, Buchmeier, Nancy, Tonge, Peter J., Xie, Lei, Bourne, Philip E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699117/
https://ncbi.nlm.nih.gov/pubmed/19578428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000423
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