Randomized, Multicenter, Phase III Trial of Heptaplatin 1-hour Infusion and 5-Fluorouracil Combination Chemotherapy Comparing with Cisplatin and 5-Fluorouracil Combination Chemotherapy in Patients with Advanced Gastric Cancer

PURPOSE: Heptaplatin (Sunpla) is a cisplatin derivative. A phase IIb trial using heptaplatin resulted in a 34% response rate with mild nephrotoxicity. We conducted a randomized phase III trial of heptaplatin plus 5-FU compared with cisplatin plus 5-FU in patients with advanced gastric cancer. MATERI...

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Detalhes bibliográficos
Main Authors: Lee, Kyung Hee, Hyun, Myung Soo, Kim, Hoon-Kyo, Jin, Hyung Min, Yang, Jinmo, Song, Hong Suk, Do, Young Rok, Ryoo, Hun Mo, Chung, Joo Seop, Zang, Dae Young, Lim, Ho-Yeong, Jin, Jong Youl, Yim, Chang Yeol, Park, Hee Sook, Kim, Jun Suk, Sohn, Chang Hak, Lee, Soon Nam
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699097/
https://ncbi.nlm.nih.gov/pubmed/19688066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2009.41.1.12
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