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Effect on Cell Cycle Progression by N-Myc Knockdown in SK-N-BE(2) Neuroblastoma Cell Line and Cytotoxicity with STI-571 Compound

PURPOSE: Neuroblastoma is a common tumor in childhood, and generally exhibits heterogeneity and a malignant progression. MYCN expression and amplification profiles frequently correlate with therapeutic prognosis. Although it has been reported that MYCN silencing causes differentiation and apoptosis...

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Главные авторы: Yu, Un-Young, Cha, Je-Eun, Ju, Sun-Young, Cho, Kyung-Ah, Yoo, Eun-Sun, Ryu, Kyung-Ha, Woo, So-Youn
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Cancer Association 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699088/
https://ncbi.nlm.nih.gov/pubmed/19688062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2008.40.1.27
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