Quantification of Normal Cell Fraction and Copy Number Neutral LOH in Clinical Lung Cancer Samples Using SNP Array Data

BACKGROUND: Technologies based on DNA microarrays have the potential to provide detailed information on genomic aberrations in tumor cells. In practice a major obstacle for quantitative detection of aberrations is the heterogeneity of clinical tumor tissue. Since tumor tissue invariably contains gen...

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Detalhes bibliográficos
Main Authors: Göransson, Hanna, Edlund, Karolina, Rydåker, Maria, Rasmussen, Markus, Winquist, Johan, Ekman, Simon, Bergqvist, Michael, Thomas, Andrew, Lambe, Mats, Rosenquist, Richard, Holmberg, Lars, Micke, Patrick, Botling, Johan, Isaksson, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699026/
https://ncbi.nlm.nih.gov/pubmed/19557126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006057
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