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Analysis of Pools of Targeted Salmonella Deletion Mutants Identifies Novel Genes Affecting Fitness during Competitive Infection in Mice

Pools of mutants of minimal complexity but maximal coverage of genes of interest facilitate screening for genes under selection in a particular environment. We constructed individual deletion mutants in 1,023 Salmonella enterica serovar Typhimurium genes, including almost all genes found in Salmonel...

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Hlavní autoři: Santiviago, Carlos A., Reynolds, M. Megan, Porwollik, Steffen, Choi, Sang-Ho, Long, Fred, Andrews-Polymenis, Helene L., McClelland, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698986/
https://ncbi.nlm.nih.gov/pubmed/19578432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000477
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