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Modification of Silk Fibroin Using Diazonium Coupling Chemistry and the Effects on hMSC Proliferation and Differentiation

A simple chemical modification method using diazonium coupling chemistry was developed to tailor the structure and hydrophilicity of silk fibroin protein. The extent of modification using several aniline derivatives was characterized using UV/vis and (1)H NMR spectroscopy, and the resulting protein...

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Detalhes bibliográficos
Main Authors: Murphy, Amanda R., John, Peter St., Kaplan, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698958/
https://ncbi.nlm.nih.gov/pubmed/18417206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.03.039
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