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Ubiquitin-Like Protein Involved in the Proteasome Pathway of Mycobacterium tuberculosis
The protein modifier ubiquitin is a signal for proteasome-mediated degradation in eukaryotes. Proteasome-bearing prokaryotes have been thought to degrade proteins via a ubiquitin-independent pathway. We have identified a prokaryotic ubiquitin-like protein, Pup (Rv2111c), which was specifically conju...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698935/ https://ncbi.nlm.nih.gov/pubmed/18832610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163885 |
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