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How to find simple and accurate rules for viral protease cleavage specificities

BACKGROUND: Proteases of human pathogens are becoming increasingly important drug targets, hence it is necessary to understand their substrate specificity and to interpret this knowledge in practically useful ways. New methods are being developed that produce large amounts of cleavage information fo...

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Detalhes bibliográficos
Main Authors: Rögnvaldsson, Thorsteinn, Etchells, Terence A, You, Liwen, Garwicz, Daniel, Jarman, Ian, Lisboa, Paulo JG
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698905/
https://ncbi.nlm.nih.gov/pubmed/19445713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-149
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