DNA polymorphism analysis of Brucella lipopolysaccharide genes reveals marked differences in O-polysaccharide biosynthetic genes between smooth and rough Brucella species and novel species-specific markers

BACKGROUND: The lipopolysaccharide is a major antigen and virulence factor of Brucella, an important bacterial pathogen. In smooth brucellae, lipopolysaccharide is made of lipid A-core oligosaccharide and N-formylperosamine O-polysaccharide. B. ovis and B. canis (rough species) lack the O-polysaccha...

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Bibliographic Details
Main Authors: Zygmunt, Michel S, Blasco, José M, Letesson, Jean-Jacques, Cloeckaert, Axel, Moriyón, Ignacio
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698832/
https://ncbi.nlm.nih.gov/pubmed/19439075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-9-92
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