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The Active Form of Human Aryl Hydrocarbon Receptor (AHR) Repressor Lacks Exon 8, and Its Pro(185) and Ala(185) Variants Repress both AHR and Hypoxia-Inducible Factor

The aryl hydrocarbon receptor (AHR) repressor (AHRR) inhibits AHR-mediated transcription and has been associated with reproductive dysfunction and tumorigenesis in humans. Previous studies have characterized the repressor function of AHRRs from mice and fish, but the human AHRR ortholog (AHRR(715))...

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Autores principales: Karchner, Sibel I., Jenny, Matthew J., Tarrant, Ann M., Evans, Brad R., Kang, Hyo Jin, Bae, Insoo, Sherr, David H., Hahn, Mark E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698758/
https://ncbi.nlm.nih.gov/pubmed/19380484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00206-09
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