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Identification of Domains Responsible for Ubiquitin-Dependent Degradation of dMyc by Glycogen Synthase Kinase 3β and Casein Kinase 1 Kinases

In the present study, we report that ubiquitin-mediated degradation of dMyc, the Drosophila homologue of the human c-myc proto-oncogene, is regulated in vitro and in vivo by members of the casein kinase 1 (CK1) family and by glycogen synthase kinase 3β (GSK3β). Using Drosophila S2 cells, we demonstr...

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Detalhes bibliográficos
Main Authors: Galletti, Margherita, Riccardo, Sara, Parisi, Federica, Lora, Carlina, Saqcena, Mahesh Kumar, Rivas, Leinny, Wong, Bonnie, Serra, Alexis, Serras, Florenci, Grifoni, Daniela, Pelicci, PierGiuseppe, Jiang, Jin, Bellosta, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698736/
https://ncbi.nlm.nih.gov/pubmed/19364825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01535-08
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