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Alendronate reduces bone toughness of ribs without significantly increasing microdamage accumulation in dogs following three years of daily treatment

Reduced bone toughness, the energy absorption capacity of the tissue, has been consistently documented in vertebrae of animals treated with a wide range of bisphosphonate doses. Data regarding toughness changes in the rib are conflicting with one report showing no effect and another showing a signif...

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Bibliographic Details
Main Authors: Allen, Matthew R., Reinwald, Susan, Burr, David B.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698704/
https://ncbi.nlm.nih.gov/pubmed/18463913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-008-9131-8
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