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Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells

ErbB4, a type I transmembrane receptor tyrosine kinase, is a member of the epidermal growth factor receptor family. Its cleavage releases an intracellular C-terminal domain (ICD), which can be either degraded following ubiqitination or translocated to the nucleus and regulate gene expression. There...

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Hlavní autoři: Zeng, Fenghua, Xu, Jie, Harris, Raymond C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Federation of American Societies for Experimental Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698660/
https://ncbi.nlm.nih.gov/pubmed/19193720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-121947
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