Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

Viral manipulation of the transduction pathways associated with key cellular functions such as actin remodeling, microtubule stabilization, and survival may favor a productive viral infection. Here we show that consistent with the vaccinia virus (VACV) and cowpox virus (CPXV) requirement for cytoske...

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Detalhes bibliográficos
Main Authors: Soares, Jamária A. P., Leite, Flávia G. G., Andrade, Luciana G., Torres, Alice A., De Sousa, Lirlândia P., Barcelos, Lucíola S., Teixeira, Mauro M., Ferreira, Paulo C. P., Kroon, Erna G., Souto-Padrón, Thaís, Bonjardim, Cláudio A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698574/
https://ncbi.nlm.nih.gov/pubmed/19386722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00245-09
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