Role of the Lymphoreticular System in Prion Neuroinvasion from the Oral and Nasal Mucosa

Prion neuroinvasion from peripheral tissues involves agent replication in the lymphoreticular system (LRS) prior to entry into the nervous system. This study investigated the role of the LRS in prion neuroinvasion from the oral and nasal mucosa in wild-type and immunodeficient mice and in hamsters i...

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Bibliographic Details
Main Authors: Bessen, Richard A., Martinka, Scott, Kelly, Jessica, Gonzalez, Daniel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698571/
https://ncbi.nlm.nih.gov/pubmed/19369351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00018-09
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