Human Parainfluenza Virus Infection of the Airway Epithelium: Viral Hemagglutinin-Neuraminidase Regulates Fusion Protein Activation and Modulates Infectivity

Three discrete activities of the paramyxovirus hemagglutinin-neuraminidase (HN) protein, receptor binding, receptor cleaving (neuraminidase), and triggering of the fusion protein, each affect the promotion of viral fusion and entry. For human parainfluenza virus type 3 (HPIV3), the effects of specif...

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Detalhes bibliográficos
Main Authors: Palermo, Laura M., Porotto, Matteo, Yokoyama, Christine C., Palmer, Samantha G., Mungall, Bruce A., Greengard, Olga, Niewiesk, Stefan, Moscona, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698534/
https://ncbi.nlm.nih.gov/pubmed/19386708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00475-09
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