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Downregulation of RUNX1 by RUNX3 Requires the RUNX3 VWRPY Sequence and Is Essential for Epstein-Barr Virus-Driven B-Cell Proliferation

Cross-regulation of RUNX1 expression by RUNX3 plays a critical role in regulating proliferation of human B cells infected with Epstein-Barr virus (EBV). When EBV infection induces RUNX3, the consequent reduction in RUNX1 levels is required for the ensuing cell proliferation because forced expression...

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Bibliografske podrobnosti
Main Authors: Brady, Gareth, Whiteman, Hannah J., Spender, Lindsay C., Farrell, Paul J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698531/
https://ncbi.nlm.nih.gov/pubmed/19403666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00216-09
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