Genetic Analysis of Hepatitis C Virus with Defective Genome and Its Infectivity in Vitro

Replication and infectivity of hepatitis C virus (HCV) with a defective genome is ambiguous. We molecularly cloned 38 HCV isolates with defective genomes from 18 patient sera. The structural regions were widely deleted, with the 5′ untranslated, core, and NS3-NS5B regions preserved. All of the delet...

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Detalhes bibliográficos
Main Authors: Sugiyama, Kazuo, Suzuki, Kenji, Nakazawa, Takahide, Funami, Kenji, Hishiki, Takayuki, Ogawa, Kazuya, Saito, Satoru, Shimotohno, Kumiko W., Suzuki, Takeshi, Shimizu, Yuko, Tobita, Reiri, Hijikata, Makoto, Takaku, Hiroshi, Shimotohno, Kunitada
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698526/
https://ncbi.nlm.nih.gov/pubmed/19369330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02674-08
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