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Autoproteolysis of YscU of Yersinia pseudotuberculosis Is Important for Regulation of Expression and Secretion of Yop Proteins

YscU of Yersinia can be autoproteolysed to generate a 10-kDa C-terminal polypeptide designated YscU(CC). Autoproteolysis occurs at the conserved N↓PTH motif of YscU. The specific in-cis-generated point mutants N263A and P264A were found to be defective in proteolysis. Both mutants expressed and secr...

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Main Authors: Björnfot, Ann-Catrin, Lavander, Moa, Forsberg, Åke, Wolf-Watz, Hans
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698497/
https://ncbi.nlm.nih.gov/pubmed/19395493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01730-08
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