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Challenging a Paradigm: the Role of DNA Homology in Tyrosine Recombinase Reactions

Summary: A classical feature of the tyrosine recombinase family of proteins catalyzing site-specific recombination, as exemplified by the phage lambda integrase and the Cre and Flp recombinases, is the ability to recombine substrates sharing very limited DNA sequence identity. Decades of research ha...

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Hlavní autoři: Rajeev, Lara, Malanowska, Karolina, Gardner, Jeffrey F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698419/
https://ncbi.nlm.nih.gov/pubmed/19487729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00038-08
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