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Development of a mariner-Based Transposon and Identification of Listeria monocytogenes Determinants, Including the Peptidyl-Prolyl Isomerase PrsA2, That Contribute to Its Hemolytic Phenotype

Listeriolysin O (LLO) is a pore-forming toxin that mediates phagosomal escape and cell-to-cell spread of the intracellular pathogen Listeria monocytogenes. In order to identify factors that control the production, activity, or secretion of this essential virulence factor, we constructed a Himar1 mar...

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Detalhes bibliográficos
Main Authors: Zemansky, Jason, Kline, Benjamin C., Woodward, Joshua J., Leber, Jess H., Marquis, Hélène, Portnoy, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698408/
https://ncbi.nlm.nih.gov/pubmed/19376879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00016-09
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