VirB Alleviates H-NS Repression of the icsP Promoter in Shigella flexneri from Sites More Than One Kilobase Upstream of the Transcription Start Site

The icsP promoter of Shigella spp. is repressed by H-NS and derepressed by VirB. Here, we show that an inverted repeat located between positions −1144 and −1130 relative to the icsP transcription start site is necessary for VirB-dependent derepression. The atypical location of this cis-acting site i...

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Bibliographic Details
Main Authors: Castellanos, Maria I., Harrison, Dustin J., Smith, Jennifer M., Labahn, Stephanie K., Levy, Karen M., Wing, Helen J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698392/
https://ncbi.nlm.nih.gov/pubmed/19363111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00313-09
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