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Role of cysteines in Plasmodium falciparum circumsporozoite protein: Interactions with heparin can rejuvenate inactive protein mutants

Various pathogenic bacteria, viruses, and protozoan bind to glycosaminoglycan-based receptors on host cells and initiate an infection. Sporozoites of Plasmodium predominantly express circumsporozoite (CS) protein on their surface, which binds to heparan sulfate proteoglycans on liver cell surface th...

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Bibliographic Details
Main Authors: Rathore, Dharmendar, McCutchan, Thomas F.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC26982/
https://ncbi.nlm.nih.gov/pubmed/10890903
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