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Bacterial Antigen Expression Is an Important Component in Inducing an Immune Response to Orally Administered Salmonella-Delivered DNA Vaccines

BACKGROUND: The use of Salmonella to deliver heterologous antigens from DNA vaccines is a well-accepted extension of the success of oral Salmonella vaccines in animal models. Attenuated S. typhimurium and S. typhi strains are safe and efficacious, and their use to deliver DNA vaccines combines the a...

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Main Authors: Gahan, Michelle E., Webster, Diane E., Wesselingh, Steven L., Strugnell, Richard A., Yang, Ji
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698147/
https://ncbi.nlm.nih.gov/pubmed/19557169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006062
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