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Chemical Genetics Reveals Bacterial and Host Cell Functions Critical for Type IV Effector Translocation by Legionella pneumophila

Delivery of effector proteins is a process widely used by bacterial pathogens to subvert host cell functions and cause disease. Effector delivery is achieved by elaborate injection devices and can often be triggered by environmental stimuli. However, effector export by the L. pneumophila Icm/Dot Typ...

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Detalhes bibliográficos
Main Authors: Charpentier, Xavier, Gabay, Joëlle E., Reyes, Moraima, Zhu, Jing W., Weiss, Arthur, Shuman, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698123/
https://ncbi.nlm.nih.gov/pubmed/19578436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000501
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