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Analysis of PDE6D and PDE6G genes for generalised progressive retinal atrophy (gPRA) mutations in dogs

The δ and γ subunits of the cGMP-phosphodiesterase (PDE6D, PDE6G) genes were screened in order to identify mutations causing generalised progressive retinal atrophy (gPRA) in dogs. In the PDE6D gene, single nucleotide polymorphisms (SNP) were observed in exon 4, in introns 2 and 3 and in the 3'...

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Bibliografske podrobnosti
Main Authors: Dekomien, Gabriele, Epplen, Joerg T
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697997/
https://ncbi.nlm.nih.gov/pubmed/12927076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-35-5-445
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