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Abnormal striatal and thalamic dopamine neurotransmission: Genotype-related features of dystonia

OBJECTIVE: To determine whether changes in D(2) receptor availability are present in carriers of genetic mutations for primary dystonia. METHODS: Manifesting and nonmanifesting carriers of the DYT1 and DYT6 dystonia mutations were scanned with [(11)C] raclopride (RAC) and PET. Measures of D(2) recep...

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Autori principali: Carbon, M, Niethammer, M, Peng, S, Raymond, D, Dhawan, V, Chaly, T, Ma, Y, Bressman, S, Eidelberg, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Academy of Neurology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697963/
https://ncbi.nlm.nih.gov/pubmed/19528516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181aa538f
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