Ketamine-induced hepatoprotection: the role of heme oxygenase-1

Lipopolysaccharide (LPS) causes hepatic injury that is mediated, in part, by upregulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Ketamine has been shown to prevent these effects. Because upregulation of heme oxygenase-1 (HO-1) has hepatoprotective effects, as does ca...

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Autors principals: Suliburk, James W., Ward, Jeremy L., Helmer, Kenneth S., Adams, Sasha D., Zuckerbraun, Brian S., Mercer, David W.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Inflammation/Immunity/Mediators
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697945/
https://ncbi.nlm.nih.gov/pubmed/19372106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00038.2009
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