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DNA Ploidy as a Surrogate to Biopsy Gleason Score for Preoperative Organ vs. Non-Organ Confined Prostate Cancer Prediction

BACKGROUND: Transformation of normal epithelium into cancer cells involves epigenetic and genetic changes and modifications in nuclear structure and tissue architecture. Nuclear morphometric alterations and clinicopathologic features were evaluated for organ vs. non-organ confined PCa prediction. ME...

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Detalhes bibliográficos
Main Authors: Isharwal, Sumit, Miller, M. Craig, Epstein, Jonathan I., Mangold, Leslie A., Humphreys, Elizabeth, Partin, Alan W., Veltri, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697847/
https://ncbi.nlm.nih.gov/pubmed/19193410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2008.09.060
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