Induction of trefoil factor (TFF)1, TFF2 and TFF3 by hypoxia is mediated by hypoxia inducible factor-1: implications for gastric mucosal healing

BACKGROUND AND PURPOSE: Mucosal microcirculation is compromised during gastric damage induced by non-steroidal anti-inflammatory drugs, such as aspirin. Consequently, oxygen supply to epithelial cells is decreased. The trefoil factor (TFF) peptides are involved in mechanisms of defence and repair in...

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Autors principals: Hernández, C, Santamatilde, E, McCreath, KJ, Cervera, AM, Díez, I, Ortiz-Masiá, D, Martínez, N, Calatayud, S, Esplugues, JV, Barrachina, MD
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697836/
https://ncbi.nlm.nih.gov/pubmed/19076725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00044.x
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