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BGC20-1531, a novel, potent and selective prostanoid EP(4) receptor antagonist: a putative new treatment for migraine headache

BACKGROUND AND PURPOSE: Prostanoid EP(4) receptor antagonists may have therapeutic utility in the treatment of migraine since EP(4) receptors have been shown to be involved in prostaglandin (PG)E(2)-induced cerebral vascular dilatation, which may be an important contributor to migraine pain. This st...

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Autors principals: Maubach, KA, Davis, RJ, Clark, DE, Fenton, G, Lockey, PM, Clark, KL, Oxford, AW, Hagan, RM, Routledge, C, Coleman, RA
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697835/
https://ncbi.nlm.nih.gov/pubmed/19154437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00027.x
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