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Persistent (current) in the face of adversity … A new class of cardiac anti-ischaemic compounds on the horizon?

Although a persistent component of the sodium current (INaP) was described in cardiac tissue about three decades ago, its physiological role and potential as a therapeutic target was not immediately apparent. Subsequent demonstrations that INaP is enhanced by hypoxia and ischaemia, and that Na(+) in...

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Hlavní autor: Saint, David A
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697828/
https://ncbi.nlm.nih.gov/pubmed/19133984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00077.x
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