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Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection

Mycophenolate mofetil (MMF), a prodrug of mycophenolic acid (MPA), is an inhibitor of inosine monophosphate dehydrogenase (IMPDH). It preferentially inhibits denovo pathway of guanosine nucleotide synthesis in T and B-lymphocytes and prevents their proliferation, thereby suppresses both cell mediate...

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Autors principals: Dalal, Pranav, Grafals, Monica, Chhabra, Darshika, Gallon, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697521/
https://ncbi.nlm.nih.gov/pubmed/19436616
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