Increased Phosphorylation of extracellular signal-regulated kinase in trigeminal nociceptive neurons following propofol administration in rats

Although propofol (PRO) is widely used in clinic as a hypnotic agent, the underlying mechanisms of its action on pain pathways is still unknown. Sprague-Dawley rats were assigned to receive PRO or pentobarbital (PEN) and were divided into two groups as LIGHT and DEEP hypnotic levels based on the EEG...

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Hauptverfasser: Shoda, Emi, Kitagawa, Junichi, Suzuki, Ikuko, Nitta-Kubota, Ieko, Miyamoto, Makiko, Tsuboi, Yoshiyuki, Kondo, Masahiro, Masuda, Yuji, Oi, Yoshiyuki, Ren, Ke, Iwata, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697496/
https://ncbi.nlm.nih.gov/pubmed/19398380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2008.11.013
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