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Cell volume and membrane stretch independently control K(+) channel activity

A number of potassium channels including members of the KCNQ family and the Ca(2+) activated IK and SK, but not BK, are strongly and reversibly regulated by small changes in cell volume. It has been argued that this general regulation is mediated through sensitivity to changes in membrane stretch. T...

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Autori principali: Hammami, Sofia, Willumsen, Niels J, Olsen, Hervør L, Morera, Francisco J, Latorre, Ramón, Klaerke, Dan A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697295/
https://ncbi.nlm.nih.gov/pubmed/19289549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163550
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