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Effects of the endothelin converting enzyme inhibitor SM-19712 in a mouse model of dextran sodium sulfate-induced colitis
Ingestion by mice of dextran sodium sulfate (DSS) induces colonic vasoconstriction and inflammation, with some of the effects potentially mediated by the vasoconstrictor endothelin-1 (ET-1). In this study, mice given 5% 40 kD DSS for 5–6 days had elevated colonic immunostaining for ET-1 and platelet...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697258/ https://ncbi.nlm.nih.gov/pubmed/19202571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20877 |
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