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Potent transcriptional interference by pausing of RNA polymerases over a downstream promoter
Elongating RNA polymerases (RNAPs) can interfere with transcription from downstream promoters by inhibiting DNA binding by RNAP and activators. However, combining quantitative measurement with mathematical modelling, we show that simple RNAP elongation cannot produce the strong asymmetric interferen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697128/ https://ncbi.nlm.nih.gov/pubmed/19524535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.04.018 |
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