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Potent transcriptional interference by pausing of RNA polymerases over a downstream promoter

Elongating RNA polymerases (RNAPs) can interfere with transcription from downstream promoters by inhibiting DNA binding by RNAP and activators. However, combining quantitative measurement with mathematical modelling, we show that simple RNAP elongation cannot produce the strong asymmetric interferen...

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Detaylı Bibliyografya
Asıl Yazarlar: Palmer, Adam C., Ahlgren-Berg, Alexandra, Egan, J. Barry, Dodd, Ian B., Shearwin, Keith E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697128/
https://ncbi.nlm.nih.gov/pubmed/19524535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.04.018
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