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Molecular Basis for the Nerve Dependence of Limb Regeneration in an Adult Vertebrate

The limb blastemal cells of an adult salamander regenerate the structures distal to the level of amputation, and the surface protein Prod 1 is a critical determinant of their proximodistal identity. The Anterior Gradient protein family member nAG is a secreted ligand for Prod 1, and a growth factor...

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Detalhes bibliográficos
Main Authors: Kumar, Anoop, Godwin, James W., Gates, Phillip B., Garza-Garcia, A. Acely, Brockes, Jeremy P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696928/
https://ncbi.nlm.nih.gov/pubmed/17975060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1147710
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