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Inhibition of MHC class I-restricted antigen presentation by γ2-herpesviruses

The γ-herpesviruses, in contrast to the α- and β-herpesviruses, are not known to inhibit antigen presentation to CD8(+) cytotoxic T lymphocytes (CTLs) during lytic cycle replication. However, murine γ-herpesvirus 68 causes a chronic lytic infection in CD4(+) T cell-deficient mice despite the persist...

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Autors principals: Stevenson, Philip G., Efstathiou, Stacey, Doherty, Peter C., Lehner, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC26969/
https://ncbi.nlm.nih.gov/pubmed/10890918
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