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The Novel Fold of Scytovirin Reveals a New Twist For Antiviral Entry Inhibitors

The solution structure of the potent 95 residue anti-HIV protein scytovirin has been determined and two carbohydrate binding sites have been identified. This unique protein, containing five structurally important disulfide bonds, demonstrates a novel fold with no elements of extended regular seconda...

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Dettagli Bibliografici
Autori principali: McFeeters, Robert. L., Xiong, Changyun, O'Keefe, Barry R., Bokesch, Heidi R., McMahon, James B., Ratner, Daniel M., Castelli, Riccardo, Seeberger, Peter H., Byrd, R. Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696897/
https://ncbi.nlm.nih.gov/pubmed/17434526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.030
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