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Circuit and Plasticity Defects in the Developing Somatosensory Cortex of Fmr1 Knock-Out Mice

Silencing of the Fmr1 gene causes fragile X syndrome. Although defects in synaptic plasticity in the cerebral cortex have been linked to cognitive impairments in Fmr1 knock-out (ko) mice, the specific cortical circuits affected in the syndrome are unknown. Here, we investigated the development of ex...

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Detalhes bibliográficos
Main Authors: Bureau, Ingrid, Shepherd, Gordon M. G., Svoboda, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696604/
https://ncbi.nlm.nih.gov/pubmed/18480274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1076-08.2008
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