Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation

CD26 is a T cell activation antigen known to bind adenosine deaminase and have dipeptidyl peptidase IV activity. Cross-linking of CD26 and CD3 with immobilized mAbs can deliver a costimulatory signal that contributes to T cell activation. Our earlier studies revealed that cross-linking of CD26 induc...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ikushima, Hideto, Munakata, Yasuhiko, Ishii, Tomonori, Iwata, Satoshi, Terashima, Masazumi, Tanaka, Hirotoshi, Schlossman, Stuart F., Morimoto, Chikao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10900005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.15.8439
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