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Microscopic factors that control β-sheet registry in Amyloid fibrils formed by 11–25 fragment of Amyloid β peptide: Insights from computer simulations
Short fragments of amyloidogenic proteins are widely used as model systems in studies of amyloid formation. Fragment 11–25 of the amyloid β protein involved in Alzheimer’s disease (Aβ11–25) was recently shown to form amyloid fibrils composed of anti-parallel β-sheets. Interestingly, fibrils grown un...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696565/ https://ncbi.nlm.nih.gov/pubmed/19414017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.058 |
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