A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury

Nitric oxide (NO(•)) competitively inhibits oxygen consumption by mitochondria at cytochrome c oxidase and S-nitrosates thiol proteins. We developed mitochondria-targeted S-nitrosothiols (MitoSNOs) that selectively modulate and protect mitochondrial function. The exemplar MitoSNO1, produced by coval...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Prime, Tracy A., Blaikie, Frances H., Evans, Cameron, Nadtochiy, Sergiy M., James, Andrew M., Dahm, Christina C., Vitturi, Dario A., Patel, Rakesh P., Hiley, C. Robin, Abakumova, Irina, Requejo, Raquel, Chouchani, Edward T., Hurd, Thomas R., Garvey, John F., Taylor, Cormac T., Brookes, Paul S., Smith, Robin A. J., Murphy, Michael P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2009
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696550/
https://ncbi.nlm.nih.gov/pubmed/19528654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903250106
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