An In Vivo Model of Reduced Nucleus Pulposus Glycosaminoglycan Content in the Rat Lumbar Intervertebral Disc

STUDY DESIGN: An in vivo model resembling early stage disc degeneration in the rat lumbar spine. OBJECTIVE: Simulate the reduced glycosaminoglycan content and altered mechanics observed in intervertebral disc degeneration using a controlled injection of chondroitinase ABC (ChABC). SUMMARY OF BACKGRO...

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Bibliographic Details
Main Authors: Boxberger, John I., Auerbach, Joshua D., Sen, Sounok, Elliott, Dawn M.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696404/
https://ncbi.nlm.nih.gov/pubmed/18197098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0b013e31816054f8
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