Pulmonary Nanoparticle Exposure Disrupts Systemic Microvascular Nitric Oxide Signaling

We have shown that pulmonary nanoparticle exposure impairs endothelium dependent dilation in systemic arterioles. However, the mechanism(s) through which this effect occurs is/are unclear. The purpose of this study was to identify alterations in the production of reactive species and endogenous nitr...

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Bibliographische Detailangaben
Hauptverfasser: Nurkiewicz, Timothy R., Porter, Dale W., Hubbs, Ann F., Stone, Samuel, Chen, Bean T., Frazer, David G., Boegehold, Matthew A., Castranova, Vincent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Systems Toxicology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696324/
https://ncbi.nlm.nih.gov/pubmed/19270016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp051
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