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IGF-II is present in bovine cornea stroma and activates keratocytes to proliferate in vitro

Extracts of bovine corneal stroma have been shown to activate keratocytes in culture to proliferate. We fractionated stromal extract on a column of Sephacryl S-300 and tested the fractions for mitogenic activity using cell culture and for the presence of IGF-II and its binding protein IGFBP-2 by Wes...

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Detalhes bibliográficos
Main Authors: Musselmann, Kurt, Kane, Bradley P., Alexandrou, Bridgette, Hassell, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696166/
https://ncbi.nlm.nih.gov/pubmed/18237730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2007.12.004
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